Immunotherapy Works in up to 75% of Cases

Allergen-specific Immunotherapy, based on the results of intradermal skin testing and/or serological testing, has been found to be effective at reducing the degree of pruritus suffered in atopic dogs by at least 50% in approximately 75% of cases. In my experience I would say that approximately 50% of cases can be kept in a reasonable state of remission without any other treatment being necessary other than flea control and improvement of skin barrier fuction with essential fatty acid supplements/spot-ons.

I use Artuvetrin immunotherapy vaccines manufactured by Artu Biologicals. Their vaccine is an alum-precipitated product, which has the advantage that clients do not have to come as frequently for injections during the build up period, only having to come initially once every 2 weeks. The risk of anaphylaxis (which is rare anyway with immunotherapy) is much less than with aqueous extract allergens.  Nevertheless, during the 2 month build-up period, clients are asked to remain at the surgery for half an hour after injection so treatment for anaphylaxis can be given immediately if it occurs (I have never seen this happen with Artuvetrin).

Since 2013 I have also been offering sublingual immunotherapy (SLIT).  This has the advantage of being simple to administer, but has to to be given twice daily, usually indefinitely.  There is some evidence that it may work slightly faster that injectable immunotherapy and some cases that have failed on injectable immunotherapy have responded to SLIT ( DeBoer 2012*). The cost of SLIT is slightly higher than  Artuvetrin injectable immunotherapy.

I have to apply for an SIC/STC from the VMD when I order immunotherapy and vaccine usually arrives within 10-14 days of ordering.

* DeBoer D, Morris M. Multicentre open trial demonstrates efficacy of sublingual immunotherapy in canine atopic dermatitis (abst). Vet Dermatol 2012;23(Suppl 1):65.